Single-use healing abutments were re-used in multiple patients after being sterilized in 184 patients at the University of Nevada – Las Vegas’s Faculty Dental Practice Clinic leading to the resignation of the director of the faculty group practice. “It’s not cost prohibitive, but it adds to the cost,” director Devore said. “Why buy something new if the thing you already have works just as well?” In addition to phoning patients, the university followed up
Tel Aviv University researcher Prof. Noam Eliaz of the TAU School of Mechanical Engineering has developed an electrochemical process for coating metal implants which vastly improves their functionality, longevity and integration into the body. “The surface chemistry, structure and morphology of our new coatings resemble biological material,” explains Prof. Eliaz. “We`ve been able to enhance the integration of the coating with the mineralized tissue of the body, allowing more peoples` bodies to accept implants.” His new coating resulted in a
Université de Montréal Researchers have modified metal surfaces such as titanium producing a sponge-like pattern of nano pits that increased growth of bone cells, decreased growth of unwanted cells and stimulated stem cells, relative to untreated smooth ones. In addition, expression of genes required for cell adhesion and growth were increased in contact with the nanoporous surfaces. “We demonstrated that some cells stick better to these surfaces than they do to the traditional smooth ones,” says Dr. Nanci. “This is
UC San Diego bioengineers and material science experts used a nano-bio technology method of placing mesenchymal stem cells on top of very thin titanium oxide nanotubes in order to control the conversion paths, called differentiation, into osteoblasts or bone building cells. Mesenchymal stem cells, which are different from embryonic stem cells, can be extracted and directly supplied from a patient’s own bone marrow. The researchers described their lab findings in a paper published this week in the Proceedings of the
Canadian researchers at the NRC Industrial Materials Institute (NRC-IMI) in Boucherville, Quebec have developed a porous titanium foam implant said to mimic a metallic version of bone. The titanium foam is made by mixing titanium powder with a polymer, and then adding foaming agents that expand the polymer when heated. Later, through a high-temperature heat treatment, the polymer is removed and the titanium particles are consolidated to provide mechanical strength to the porous structure. Porous titanium had previously been used
Over the course of evolution mussels have developed a special glue that not only works under water, but is also a particularly firm and lasting bonding agent. The strength of the bond is due to a particular protein. Dr. Klaus Rischka, a chemist at the Fraunhofer Institute for Manufacturing Engineering and Applied Materials Research IFAM in Bremen and his partners at Frankfurt University Hospital, the Center of Biotechnical Engineering BitZ at Darmstadt University of Technology, the State Materials Testing Institute
Dentsply Friadent had released their next generation implant surface which features a thermal etching process called BioPoreStructuring. They claim the specific etching acid they use creates an ideal physical, chemical and biological surface needed to attract osteoblasts to the implant surface.
Bicon have developed a new surface process, NanoTite™. A high-energy ion beam source aims a beam of ions at the surface of a target treated with HA. These high-energy ions eject the HA from the target/substrate and create a molecular cloud whose molecules bond with the surface of the Bicon Ti 6Al-4V ELI implant. This Ion-Beam Assisted Deposition process, which provides increased integration with the implant surface, is known as High-Energy Sputter Deposition. Using an Ion-Beam Assisted Deposition process, the
Ulf Wikesjö of the Medical College of Georgia has demonstrated impressive osseous regeneration around dental implants coated with recombinant human Bone Morphogenic Protein (rhBMP-2). Dr. Wikesjö is researching wound-healing and tissue regeneration with a $1.4 million grant from Nobel Biocare. In laboratory tests, rhBMP-2 applied onto implants directs endogenous stem cells to become bone-forming cells. The result was a nearly complete regeneration of lost tissue. He hopes to start clinical trials in the summer of 2006.
Brown University engineers have shown that both zinc and titanium oxide nanosurfaces can reduce the presence of bacteria. Discs with nanostructured surfaces had bumps that measured only .023 microns in diameter. Discs with microstructured surfaces had bumps that measured about 5 microns in diameter. Microstructured zinc oxide discs were host to 1,000 times more bacteria than the nanostructured zinc oxide discs. Similar, but less striking, results were duplicated on titanium oxide discs. The engineer`s hypothesis is that: `with the nanostructured
Straumann has received a US patent for a bioactive coating for their implants. Their modified sandblasted and acid-etched (SLA) surface is coated with an Arg–Gly–Asp (RGD)-peptide-modified polymer (PLL-g-PEG/PEG–RGD). According to a study by Danny Buser, RGD-coated implants demonstrated significantly higher percentages of bone-to-implant contact as compared with controls at 2 weeks. The hypothesized mechanism is that the attachment of RGD peptides directed towards integrin receptors on the PEGylated surface promotes adhesion of cells of mesenchymal origin e.g. osteoblasts to the
Nobel Biocare makes mention of their new all-ceramic implant design that uses a zirconium based surface in their annual report (page 35). Clinical trials are in progress. It seems interest in Zirconium Oxide based implants is on the rise by the big companies. Definitely a trend to keep an eye on.
Nobel Biocare has introduced an improvement to their Ti-Unite Surface. By placing micro grooves on the surface they claim to increase the implant stability by up to 30% thereby allowing for more rapid bone formation. This surface improvement takes a mechanical approach to increase Bone-to-Implant Contact as opposed to the chemical surface modification`s introduced by Astra (Osseospeed) and Straumann (SLAtive), their main competitors.
Straumann has introduced an improvement in their SLA implant surface. SLActive is based on the scientifically proven SLA® surface topography, but exhibits a fundamentally improved surface chemistry. Due to its ideal conditioning, the chemically active and hydrophilic SLActive surface significantly promotes the osseointegration process. Animal studies demonstrate that their new surface allows for accelerated bone remodelling during the entire osseointegration process.