Cerapedics Develops Peptide Coated Bone Grafting Material

Cerapedic`s i-FACTOR bone graft is the only biologic bone graft that combines a unique anorganic bone mineral (ABM) and small peptide (P-15™) to act as an attachment factor for specific integrins on osteogenic cells. This novel mechanism of action enhances the body’s natural bone healing process resulting in safe, predictable bone formation at a lower cost than growth factors. ABM/P-15 has been in human clinical use for more than thirteen years in an estimated 500,000 patients worldwide. P-15 is a synthetic fifteen amino acid peptide that mimics the cell-binding domain of Type I human collagen and is responsible for osteogenic cell attachment to Type 1 human collagen.

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