Over the course of evolution mussels have developed a special glue that not only works under water, but is also a particularly firm and lasting bonding agent. The strength of the bond is due to a particular protein.
Dr. Klaus Rischka, a chemist at the Fraunhofer Institute for Manufacturing Engineering and Applied Materials Research IFAM in Bremen and his partners at Frankfurt University Hospital, the Center of Biotechnical Engineering BitZ at Darmstadt University of Technology, the State Materials Testing Institute MPA and the implant manufacturer Straumann in Freiburg will initially demonstrate the glue`s suitability on the basis of a dental implant made of titanium.
It is current practice to anchor tooth implants in the jaw bone without an adhesive. This often leaves gaps between the gums and the metal, allowing bacteria to enter and cause infections. A glue that firmly connects the gums to the implant would serve as an effective barrier against aggressive germs.
Conventional products are not suited to such a purpose, however, as they would sooner or later dissolve in the moist environment inside the mouth.
The use of this substance in medical applications requires an additional ingredient: a growth protein, which can likewise be synthetically produced using the classic technique of solid-phase peptide synthesis. Its purpose is to stimulate cell growth so that the body`s own tissue -in this case the gums – bonds as closely as possible with the implant.